Lithium Strengthens Cells in the Brain


Lithium strengthens cells in the brain.

You always knew you were special – most of us have many positive qualities – and that being diagnosed with Bipolar 1 Disorder in your late teens or early adulthood may also mean you have a good dose of intelligence packed into that noggin of yours; even be smarter than most others.

Lithium Strengthens Cells in the Brain
You are Now a Badass Bipolar Ninja. No More Slouching Please…

But did you know you were a ninja in training?

Destined to enter into a special zone – the psych void – and be treated by brilliant physicians who are going to put that brain of yours that went haywire on a map that hasn’t even been drawn yet?


Due to Death From Toxicity Lithium Was Banned From Use in U.S. Until 1970. Click To Tweet

You will surpass the stratosphere, reach mental heights never observed before and… wait, this is the best part: get a drug that is going to make the brain cells they think are causing this craziness even stronger. Stronger!

No more weak bipolar brain cells. No sirree. This illness is not for the meek, you know. It’s for ninjas!

You will be prescribed drugs to help in this process as we all know the world needs more ninjas. More smart folks like you with super powers of the brain and that brain needs to be fortified with… wait for it… the bionic-empowered salt lithium.

Related post: Neuroprotective Properties of Lithium.

Seriously, is that not the coolest thing ever?

How Was Lithium Discovered?

An Australian psychiatrist – John Cade, M.D. – happened upon it by chance in 1949 by doing experiments with mentally ill persons urine and guinea pigs. The very short version is that he discovered the urine from the mentally ill made the small mammals die faster than urine from normal persons.

He postulated the reason for this difference was the mentally ill persons had high concentrations of uric acid in their urine. You may think of gout when you hear the term uric acid and you would be correct. But we are talking about bipolar.

So what did Dr. Cade then discover?

He added some things to the solution he was injecting into the guinea pigs to test his hypothesis and to try to increase the water solubility of the urine and make it less toxic (so the little guys wouldn’t die as quickly).

One thing he played around with was lithium ion. He found lithium ion had a calming effect and surmised it may have the same effect on humans.

He took a little himself and experienced the same effect, so went on to give it to patients and the rest, as they say, is history.

Note: lithium was used in psychiatry before this discovery by Dr. Cade and after his discovery the new miracle drug (but of course, only miracles create ninjas you know…) caused many patient deaths due to toxicity. Source: John Cade.

Does Lithium Strengthen Brain Cells?

How miracles go, besides creating badass ninjas, is that they fade away or become more prominent, more miraculous. That’s happened with lithium and the treatment of bipolar disorder.

Now that if they need to prescribe a high dose there are blood tests that can determine if you are becoming toxic and drug companies have patents for more forms of it… it’s become better than just having an observable therapeutic effect.

Note: That is what lithium does – gives a calming effect. It does not correct any imbalance in your brain. Re-read this please if you still are thinking that and if so I am going to have to take away your ninja certificate. Hmmmph. What is the Chemical Imbalance Theory?

Now, not only is lithium as a drug warranted for use in the treatment of Bipolar 1 Disorder it is said to have identifiable positive effects on your brain cells.

It makes them stronger maybe, or encourages their growth. Learn more here: Neuroprotective Properties of Lithium.

Many are Intolerant to Lithium Treatment

Lithium is the treatment of choice for bipolar, but this illness is not simply a biological state of ‘lithium-deficiency’ in your brain and body.

Like me, some are intolerant to the treatment. I was given lithium twice for bipolar – once for a year at a dose needing blood monitoring – and my condition worsened.

I did not become manic while on the med but it led to a significant increase in depression creating a serious depressive episode with suicidal ideation – not fun and it was awful.

After I went off lithium treatment and ended care with the non-ninja psychiatrist, I improved.

I also ended-up hospitalized a few times in the years that followed. It can be hard to avoid that when you are Manic Depressive and I was not, unfortunately, an exception to that general rule.

It’s a bitch of an illness, a pretty horrific illness at times – suitable only for true to form real life badass ninjas.

If you want to know some potential side effects from taking lithium here is a good source that separates them into categories also (less common, common, rare) including a section on what happens if you overdose on lithium: Side Effects.

A Ninja I am Not – My Brain and Body Were Simply Sick

Let’s understand this illness better – and get at the root causes so treatments can be given that can help a sufferer heal.

We know for certain now it is not a lithium-deficiency causing things to go on in the body that then contribute to some of its pathological states… but that lithium can help control these out of control or extreme states.

What other things can have this effect i.e. cause severe depression or mania? What is really going on in the body? It’s crucial work. We all know the world needs more ninjas.



  1. Waltstawicki. said:

    Only, we are seeing even SSRI with neuroprotective side effects. A number of cannabinoids, from cannabis plants, other plants or lab s also have neuroprotective properties. Why, big bad morphine is on the list,!

    The more data, the more confusing it all is.

    I humbly suggest those who say it grows new neurons are somewhat wrong. At most it down regulates pruning and programmed cell death.

    As for causes? Math , as in game of life (the other one, not the silly online one) demonstrate smallinput setting changes can lead togreat outcome

    December 29, 2016
    • Molly said:

      I haven’t read of anything that says that SSRI’s have “neuroprotective side effects”.

      Do you have any links to published studies? That would be a bit absurd in theory. The medications disrupt biological processes… side effects are what the person who ingests the toxic substance experiences as a result of that disruption. Effects that occur from the changes induced by the medication.

      They treat nothing (that is identifiable). Short-term positive response reported by a patient is primarily a placebo effect. Causes changes in functioning (just like if you took a few shots of tequila) but is not treating anything, correcting anything.

      Related post: Placebo Effect of Antidepressants.

      December 29, 2016
      • Molly said:

        And I should add to the above – I have read the ‘neuroprotective’ stuff, but I bet a little digging would show it for what much of this research is that ignores the harm caused by a medication and makes up ‘theories’ to try and support contiued use of the drug and more similar drugs… is Big Pharma agenda research.

        If lithium has been seen to ‘protect’ anything in the brain, what’s the value? It is not correcting any identifiable biologic process in the body – it is a major mood stabilizer/tranquilzer to counteract symptoms – and causes very serious side effects.

        Neuroprotective of what?

        Who (other than Big Pharma) cares if some neuron is somehow being bathed in toxic substances that make it resistent to some bs they’ve used in a study (more toxins? exposures? damage from other psych meds?) – when it is being given as they are ignorant to the actual underlying biological causes of the illness.

        Alcohol can have beneficial effects – do doctors prescribe the use of alcohol to treat some illness they don’t understand very well, but may help in some ways. No.

        December 29, 2016
        • Molly said:

          Next post about ‘neuroprotective qualities of psych meds (lithium, SSRIs)’ – maybe I’ll change my mind. Highly doubt it.

          December 29, 2016
  2. Talon said:

    ::Ninja High Five!!!:: Great Article!

    November 12, 2016
    • Molly said:

      LOL & than you! Glad you liked it.

      November 13, 2016
  3. Anne said:

    Hi Molly,
    I find this post very interesting. I know from the research that Lithium is the only bipolar med that is neuroprotective, which is why I take it. Bipolar steals enough of my brain cells as it is. I have had some of the not so nice side effects of Lithium, such as tumours on my parathyroid glands, thyroid goitre, a horrible episode of severe double vision and weight gain. Still I choose to take the Lithium – meds over madness is the choice I make twice a day.

    June 27, 2016
    • Molly said:

      It is definitely the treatment of choice, and for good reason, though many are intolerant to it like I was (high doses for a year). It is a horrible illness. We need better understanding of root causes, and more treatment options that are less toxic, so sufferers do not have to suffer additional illness issues like you describe above.

      Such a difficult issue, yet there is no reason why we cannot have better understanding (and teach folks that truth about the Chemical Imbalance Theory so they can make educated choices based on correct information) of the illness and more effective, less harmful treatments.

      It’s starting to happen, I have hope. Glad you’ve found things to help you live and enjoy life. Hugs.

      June 27, 2016

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