Do bipolar patients really have toxic blood?
Meaning… were they (and me) born with some genetic variation that creates at some point in their life formation of blood cells and blood plasma that has a negative effect on the ability of neurons to connect with other neurons like normal neurons should?
Is it even possible to study this hypothesis… when blood samples used are from test subjects who have been exposed to large doses of toxic psychotropic medications?
Medications that are known to adversely affect neural connectivity?
[bctt tweet=”Researchers Claim Bipolar Patients Have Toxic Blood But Fail to Account for Toxic Meds.”]
The below is from a study on SSRI antidepressants and neural connectivity by Max Planck from the Institute for Human Cognitive and Brain Sciences:
“The study detailed the fact that just one dose of an antidepressant can cause significant functional changes within the human brain.”
Just one dose! And the psychotropic medication affects neural functioning in the brain. Nothing to do with the test subjects genetic profile, or proven to be related. And it’s complicated.
The results of the study showed that taking an SSRI essentially reduces the amount of neural connectivity within the brain – with the notable exception of two specific parts: the cerebellum and the thalamus. The team of researchers observed decrease in connectivity throughout most areas of the brain.
“However, they did find that in the cerebellum and thalamus, the opposite effect occurred and connectivity actually increased.”
More Bipolar Research Indicating Damage from Medications, Not Genetic Susceptability
The heading for this article on Science Daily.com piqued my interest: “Ever-changing Moods May be Toxic to the Brain of Bipolar Patients“.
First off, ever-changing moods are not necessarily bipolar disorder. In general, the illness is episodic in nature with periods of normal functioning in-between illness states.
From my understanding, contantly-changing moods, daily mood instability that is persistent and causes difficulties in a person’s life is more characteristic of Borderline Personality Disorder (BPD). In the UK, BPD is actually called “Bipolar Affective Disorder“.
Adding yet more confusion to the understanding of, targeted research for and development of new, non-harmful treatment modalities for actual Manic Depressive illness – now called “Bipolar 1 Disorder”.
But drug companies, universities, physicians and researchers like the below do get to make a lot of money.
Research Does Not Show Any Genetically Defective Toxic Blood
So what did this study supposedly show?
“The brain of bipolar patients shows changes such as reduction in volume and neuroprogression. The latter is a pathological version of an otherwise normal mechanism by which the brain re-writes its neuronal connections, a process that is associated to learning, memory and even recovery from brain damage.”
“In bipolar patients, the process is associated with loss of neuron connections and clinical and neurocognitive deterioration.”
Yes… brain damage from psych meds.
No – it is not the patient (and therefore an inherent vulnerability in their genetic profile) that is causing this ‘pathological version’ – it is the MEDICATIONS they have been prescribed. Most likely.
Either way, you cannot in any way make the claim these unethcial and my guess – paid for by Big Pharma funds – researchers are claiming to make. So that Big Pharma – and the physicians who prescribe them – do not get held accountable for the damage the meds have caused.
Bipolar Research Often Deceptive Big Pharma Propaganda
What did the researchers do to come up with such a ‘discovery’?
“…exposed differentiated neurons to blood serum from either healthy normal individuals or bipolar patients. The group then observed that neurons exposed to serum from bipolar patients had a significant loss in the density of neurites, which is used to estimate the number of neuron connections, if compared to neurite density of neurons exposed to serum from healthy individuals.”
Using Patients Damaged by Medications to Support a Lie
The researchers left out some really, really important stuff – like… how many psychotropic medications have these bipolar patients been put on? And, what are the known effects of thse meds on neural connectivity and functioning in the brain?
How many meds? For how long? Years, months… they obviously have been in treatment if they’ve been identified as ‘patients’ and were selected for the study.
I gave you one current study above, that shows changes with just ONE DOSE of an antideprssant. What do you think would be seen with chronic use of one or multiple psychotropic meds? Any guesses?
Are These Results Valid? When the Changes Are Most Likely Due to Toxic Medications?
I’d love to believe in this scientific hokey pokey, if I didn’t already know better.
This entire study should be thrown out, as it does not indicate ANY inclusion of the effects from toxic psychotropic medications the bipolar patient study group was on, or had been on.
And the research is unethical. But that’s me. Let’s read their final claims and get more clues about the agenda behind the research.
“Future studies should focus on finding drugs that can protect BD brain cells from the toxic effects of their own blood.”
Develop more drugs, but of course. And here’s what they claim they’ve discovered:
“Our results indicate that the blood of BD patients is toxic to brain cells and affects the connectivity ability of neurons.”
“Considering our previous knowledge on the association between mood episodes and blood toxicity, we believe that the more episodes a patient has, the more cellular components are produced that impair the brain’s ability to deal with environmental changes, inflammation and stress,” says Klamt.
Another way to look at the proposed results? That a person who has more episodes, will have been exposed to more toxic drugs. That in many cases they never needed in the first place. Sickening.
And again – the researchers never clarified whether the bipolar subjects in the study were ON MEDICATIONS at the time the blood was drawn that was examined.
Two Gold Stars for Trying, Let’s Try Harder
I’m stingy in gold star ratings – but trying to be nice.
Maybe this study could be re-evaluated with accurate information about medications in the body then used to understand how these meds work i.e. making bipolar patients blood sick and toxic. That’d be ethical and honest.
To accurately study the blood and make distinctions between normal people and bipolar folks you would have to have comparative samples – meaning, similar or without enough differentiation that could account for the end results in and of itself.
Or you would have to somehow account for the reality of toxic medications in the system of the patient study group.
This study did neither. Is simply more Big Pharma-funded science that gets more money devoted to creating more toxic drugs.
And more brain damaged ‘patients’. Hopefully this will stop at some point.
Related post: Will Turmeric Help Your Depression?
I’d rather focus on that. Cheers.